News
Dr. Ichiro Akagi's research was published in the American journal Biochemical and Biophysical Research Communications
A study on microRNA in esophageal squamous cell carcinoma conducted by Ichiro Akagi (Doctor/PhD) of the Gastroenterology Department at our clinic and the Department of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, was published in the American journal Biochemical and Biophysical Research Communications (May 2018, 5).
[Research title]
"MiR-141-3p targets PH Domain Leucine-Rich Repeat-Containing Protein Phosphatase 2 (PHLPP2) in esophageal squamous cell carcinoma and regulates the oncogenic PI3K-AKT pathway."
The microRNA levels in esophageal squamous cell carcinoma cell lines and normal esophageal squamous cell human cell lines were compared and the following results were obtained:
It has been reported that miR-141-3p may be a biomarker for colorectal cancer, prostate cancer, and breast cancer, but it has also been suggested that it may be a new biomarker for esophageal squamous cell carcinoma. These findings will be presented at the American Association for Cancer Research (AACR) Annual Meeting 2019 to be held in Atlanta, Georgia, USA in 2019.
*The content of this page is current as of July 2018, 6.